From discovery to impact

Success stories in medical innovation

Lead-to-Impact section 2026 issue 1

The story behind a new medical treatment is usually an epic that unfolds over more than a decade.

It often begins with the high of a fundamental insight, then moves through the hazards of preclinical studies, fundraising, regulatory hurdles and clinical trials.  

There are milestones worth celebrating along the way, but setbacks are common — and most innovations never reach the clinic. Still, some of these tales do have a happy ending, delivering new therapies, devices and diagnostic tools that advance patient care.

The articles that follow in our Impact section of the latest Stanford Medicine magazine issue feature a few of those success stories, told through conversations with Stanford Medicine researchers whose innovations are making an impact today.

Impact

A heart-protective mutation in a pill

Genetic insights lead to a new treatment for cardiomyopathy

An ointment to quell atopic dermatitis

Quieting the intense itch of a common skin condition

A tool to diagnose sepsis

Speeding the time to treatment when minutes matter

A pacemaker for the brain

Treating Parkinson’s by responding to the brain’s rhythms in real time

Gene therapy for epidermolysis bullosa

Providing long-term relief from a debilitating skin blistering disease